I will be the first to admit that I make a spelling error every now and then. Normally they occur when I'm typing a bit too hastily. Perhaps I'm a little too arrogant to use the spell-check function, but I don't like the way that most of them insist that I use the American spelling of certain words.
The vast majority of spelling errors are pretty harmless. We know what people mean anyway. A lot of people think "a lot" is one word, so you see alot of errors surrounding the use of those two little words. Over time I have started to lose my eagle eye for unimportant errors, and quite often I don't notice when people substitute the word loose for lose. Perhaps I'm loosing my uptight attitude about this subject. After all, glass houses and such.
I blog, and I like reading other blogs, but I'm certain that the blogosphere has brought about a situation unlike any other in the history of communication, whereby never before have so many people with so little to say have an opportunity to say so much. This will certainly impact the quality of what we read.
Some errors might change the entire meaning of the message that the writer is trying to convey, but these are few and far between. For the most part, it's just a tiny little speck in the overall picture, a harmless little faux pas. I certainly wouldn't lose any frinds over this issue, after all nobody is perfect.